Pathogenesis ofCandida albicansbiofilm

Frozen shoulder: Pathogenesis, Diagnosis and Treatment

Frozen shoulder (FS) or adhesive capsulitis is a common disease which causes pain, difficulty and restriction in the movement of the shoulder joint due to unclear complex etiology. The everyday tasks such as bathing, dressing and driving become difficult. It affects both men and women especially in their 40s and 60s. The duration of the disease varies from one patient to another and it may last...

The Immunological Basis in the Pathogenesis of Gout

Pathogenesis of Epilepsy: Challenges in Animal Models

  Epilepsy is one of the most common chronic disorders affecting individuals of all ages. A greater understanding of pathogenesis in epilepsy will likely provide the basis fundamental for development of new antiepileptic therapies that aim to prevent the epileptogenesis process or modify the progression of epilepsy in addition to treatment of epilepsy symptomatically. Therefore, severa...

Distribution and Antifungal Susceptibility ofCandida Species Isolated from Clinical Specimens at the University Teaching Hospital, Lusaka, Zambia

-Background:Candida species have emerged as successful pathogens worldwide and are associated with immunocompromised patients. Additionally, there is increasing resistance of Candida species to antifungal agents, and this has greatly contributed to the high morbidity and mortality amongst affected patients. In Zambia, little is known about the distribution of Candida species and their antifunga...

Pathogenesis of Atopic Dermatitis: Current Paradigm

Atopic dermatitis (AD) is characterized by skin inflammation, barrier dysfunction and chronic pruritus. In this review, recent advances in the pathogenesis of AD are summarized. Clinical efficacy of the anti-IL-4 receptor antibody dupilumab implies that type 2 cytokines IL-4 and IL-13 have pivotal roles in atopic inflammation. The expression of IL-4 and IL-13 as well as type 2 chemokines such a...